Grants

VI Medrx, LLC. Fibroblast responses to three nanomaterial enhanced bioscaffolds: An in vitro assessment.

UM System Research Board. Biomarkers for spontaneously occurring osteoarthritis.

Connective Orthopaedics. Canine ACL augmentation study.

Pfizer, Inc. Effect of compound PF-01322574 on cartilage degeneration in the canine ACLt model.

Veterinary Orthopaedic Society Hohn-Johnson Grant. Comparison of imaging modalities for diagnosis and treatment decision making for shoulder osteochondrosis in dogs.

Stryker, Inc. In vivo testing of BioDuctTM Meniscal Fixation Devices in an avascular meniscal tear model in dogs.

Iams. Evaluation of two nutriceuticals using a feline in vitro osteoarthritis model. Phase 1 – Evaluation of Boron and one Fatty-Acid.

Musculoskeletal Transplant Foundation. Physiologic loading for long-term maintenance of osteochondral grafts in culture.

Ethicon Endo-Surgery. Comparing effects of radiofrequency and harmonic instruments on meniscal tissue.

Iams Company. Evaluation of two nutriceuticals using a feline in vitro osteoarthritis model.

National Institutes of Health. A novel mechanism for intra-articular nonunion.

Iams Company. Evaluation of four chondroprotective nutriceuticals using an in vitro osteoarthritis model.

Pfizer. Comparison of animal models of osteoarthritis.

Orthopaedic Trauma Association. Trans-sacral/Alar screw fixation for comminuted transforaminal sacral fractures.

US Army Institute of Surgical Research. Modification of an accepted animal model of osteomyelitis to simulate and evaluate treatment of war extremity wounds.

Iams Company. Feasibility study for development of an in vitro osteoarthritis model for cats.

Iams Company. Evaluation of addition of adult canine serum to an in vitro osteoarthritis model for evaluation of chondroprotective nutriceuticals.

Pfizer. Effect of 10 mg/kg, BID, PF-667 on Cartilage Degeneration in the Canine ACLt Model.

Arthrex. Design and validation of a bone-tendon allograft for rotator cuff repair.

University of Missouri Phi Zeta. Correlating magnetic resonance imaging, arthroscopy, and hyaluronan content in synovial fluid to diagnose the presence and severity of osteoarthritis in the canine stifle.

VOS Hohn-Johnson Grant. Chondrogenic differentiation of normal versus osteoarthritic synovium using sequential exposure of growth factors for fibrocartilage tissue engineering.

National Institutes of Health. Tissue engineered osteochondral patella resurfacing.

National Institutes of Health. Matrix Metalloproteinase Inhibition and Specificity.

Iams Company. Evaluation of chondroprotective nutriceuticals in an in vitro osteoarthritis model: phase 2-4

BioDuct LLC. The effects of BioDuct cellular conduits versus conventional trephined access channels and static compressive force on cellular delivery and distribution in an in vitro three-dimensional culture model of avascular meniscal injuries.

BioDuct LLC. In vivo testing of BioDuct in an avascular meniscal tear model in dogs.

American College of Veterinary Surgeons. The effects of cyclic tensile load on gene and protein expression patterns in canine cranial cruciate ligamentocytes.

Musculoskeletal Transplant Foundation. Comparison of tissue-engineered osteochondral grafts fabricated with mesenchymal stem cells and bioactive glass or allograft bone.

Zimmer. Comparison of tissue-engineered osteochondral grafts fabricated with mesenchymal stem cells and trabecular metal of allograft bone.

Univeristy of Missouri COR. An in vitro model to study the effects of corticosteroids on articular cartilage subjected to dynamic compressive load.

University of Missouri COR. Avascular meniscal fibrocartilage regeneration utilizing synoviocyte-seeded synthetic scaffolds cultured under the effects of transforming growth factor, fibroblast growth factor, and biomechanical stimulus.

Schwartz Biomedical. Evaluation of the BioDuct device for in vivo healing of avascular meniscal tears.

Schwartz Biomedical. Evaluation of the BioDuct device in an in vitro avascular meniscal tear model. American Kennel Club. Molecular analysis of contributory factors of osteoarthritis in canine hip dysplasia.

University of Missouri COR. Molecular analysis of contributory factors of osteoarthritis in equine degenerative joint disease.

University of Missouri COR. Evaluation of intra-articular administration of botulinum toxin type A for treatment of equine arthritis.

University of Cincinnati OREF. The Use of Small Intestine Submuscosa as a scaffold in Flexor Tendon Repair.

University of Cincinnati OREF. Repair of Type II SLAP Lesion: A biomechanical analysis for critical site of anchor placement.

DePuy Orthopaedics, Inc. Use of small intestinal submucosa (SIS) for tissue-engineered replacement of posterior meniscal defects in dogs: Part 4.

DePuy Orthopaedics, Inc. In vivo biological responses of Restore and competitive devices used for abdominal wall repair.

Iams Company. Evaluation of chondroprotective nutriceuticals in an in vitro osteoarthritis model.

IMEX Veterinary Inc. Testing of tissue anchors for veterinary application.

DePuy Orthopaedics, Inc. In vitro determination of cell viability and cell retention properties of 4 different biomaterials used for orthopaedic tissue engineering.

DePuy Orthopaedics, Inc. Evaluation of SIS for instrasubstance muscle laceration repair. National Institutes of Health. Mechanism of MMP gene induction in osteoarthritis.

University of Missouri CVM Committee on Research Grant. An in vitro model of osteoarthritis: Optimization of peak dynamic compressive stress and loading frequency.

DePuy Orthopaedics, Inc. Use of small intestinal submucosa (SIS) for tissue-engineered replacement of posterior meniscal defects in dogs: Part 3. Orthopaedic Trauma Association. The role of anabolic supplementation to enhance the soft tissue envelope in fracture healing.

DePuy Orthopaedics, Inc. Use of small intestinal submucosa (SIS) for tissue-engineered replacement of posterior meniscal defects in dogs.

United States Department of Agriculture. Comparison of two in vitro cell culture techniques as models of equine osteoarthritis and examination of biochemical responses of equine chondrocytes using these models.

Merck-Merial Research Training Grant. Mesenchymal stem cell culture for orthopaedic tissue engineering.

DePuy Orthopaedics, Inc. Use of small intestinal submucosa (SIS) for tissue-engineered replacement of posterior meniscal defects in dogs: Addition of non-weight-bearing slings and hyaluronic acid.

DePuy Orthopaedics, Inc. Assessment of proteins naturally eluted from porcine small intestinal submucosa.

Orthopaedic Trauma Association. Anabolic enteral supplementation for fracture healing in a rat model.

DePuy Orthopaedics, Inc. The use of SIS scaffolds (with platelet-rich plasma) for the healing of avascular meniscal defects in a canine model.

DePuy Orthopaedics, Inc. Use of small intestinal submucosa (SIS)) for tissue-engineered replacement of vascular meniscal defects in dogs.

Musculoskeletal Transplant Foundation. In vivo assessment of a cortical bone allograft tissue anchor.

University of Nebraska Medical Center. Effects of applied force on tissue-engineered cartilage.

Veterinary Product Laboratories. Evaluation of a synthetic glucosamine in an in vitro osteoarthritis model.

Veterinary Orthopedic Society, Hohn-Johnson Research Award. $9,950. Characterizing osteochondrosis in the dog: The roles of matrix metalloproteinases and biomechanical stress.

Johnson & Johnson (DePuy Orthopaedics, Mitek Products. The use of biological scaffolds (with and without platelet-rich plasma [PRP]) for the healing of avascular meniscal defects in a canine model.

Bayer Animal Health. FlexCell Compression Bioreactor for In Vitro Osteoarthritis and Tissue Engineering.

DePuy Orthopaedics, Inc. Use of SIS for repair of avascular posterior meniscal flap defects in dogs.

DePuy Orthopaedics, Inc. In vitro determination of chemotactic, mitogenic, and cell retention properties of SIS for use in meniscal tissue engineering.

Sulzer Biologics. Growth factor enhancement of meniscal healing in avascular meniscal defects in dogs.

DePuy Orthopaedics, Inc. Use of SIS for replacement of large avascular meniscal defects in dogs, part I.

DePuy Orthopaedics, Inc. Use of SIS for replacement of large avascular meniscal defects in dogs, part II.

Musculoskeletal Transplant Foundation. In vitro evaluation of two tissue anchors for rotator cuff repair.

Cook Biotech, Inc. The use of small intestinal submucosa for repair of pelvic diaphragm weakness in dogs.

DePuy Orthopaedics, Inc. SIS induction of meniscal regeneration in dogs, Phase II.

DePuy Orthopaedics, Inc. Comparison of SIS grafts for meniscal regeneration in dogs.

Pfizer, Inc. Evaluation of plasma, synovial fluid, and urine markers in osteoarthritic dogs.

Pfizer, Inc. Evaluation of plasma, synovial fluid, and urine markers in healthy dogs.

University of Missouri-Columbia, Teaching Enhancement Award. Surgery CDs.

University of Missouri-Columbia College of Veterinary Medicine, Committee on Research Grant. Role of matrix metalloproteinases in naturally occurring canine chondrosarcoma.

University of Missouri-Columbia Department of Veterinary Medicine and Surgery, Committee on Research Grant. Material properties of the canine meniscus.

University of Missouri-Columbia College of Veterinary Medicine, Committee on Research Grant. Effects of TIMP-1 and TIMP-2 on canine chondrocytes in three-dimensional culture.

University of Missouri-Columbia Department of Veterinary Medicine and Surgery, Committee on Research Grant. Biosynthetic effect of a m-opioid agonist on canine chondrocytes in three-dimensional culture with and without the influence of interleukin-1.

Phi Zeta. Immunohistochemical demonstration of cytokeratin subsets in canine synovial sarcomas.

University of Missouri-Columbia Committee on Research, Special Canine Research Grant. Design and testing of a canine total elbow arthroplasty system.

University of Nebraska Medical Center, College of Dentistry Research Committee Grant. Tissue engineering of human hyaline cartilage: A preliminary study.